LRP6 holds the key to the entry of anthrax toxin

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Authors
Bann, James G.
Cegelski, Lynette
Hultgren, Scott J.
Issue Date
2006-03-24
Type
Article
Language
eng
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Abstract

In this issue of Cell, it is demonstrated that the low-density lipoprotein receptor-related protein 6 (LRP6) promotes endocytosis of the anthrax toxin into cells. LRP6 acts as a coreceptor with either TEM8 or CMG2, the two previously identified receptors for anthrax toxin.

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Citation
Cell. 2006 Mar 24; 124(6): 1119-21.
Publisher
Elsevier
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ISSN
0092-8674
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