LRP6 holds the key to the entry of anthrax toxin

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Authors
Bann, James G.
Cegelski, Lynette
Hultgren, Scott J.
Advisors
Issue Date
2006-03-24
Type
Article
Keywords
Comment , Review
Research Projects
Organizational Units
Journal Issue
Citation
Cell. 2006 Mar 24; 124(6): 1119-21.
Abstract

In this issue of Cell, it is demonstrated that the low-density lipoprotein receptor-related protein 6 (LRP6) promotes endocytosis of the anthrax toxin into cells. LRP6 acts as a coreceptor with either TEM8 or CMG2, the two previously identified receptors for anthrax toxin.

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Description
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Publisher
Elsevier
Journal
Book Title
Series
Cell
Cell
PubMed ID
DOI
ISSN
0092-8674
EISSN