We present new νμ → νe, νμ → νμ, ν¯μ → ν¯e, and ν¯μ → ν¯μ oscillation measurements by the NOvA experiment, with a 50% increase in neutrino-mode beam exposure over the previously reported results. The additional data, combined with previously published neutrino and antineutrino data, are all analyzed using improved techniques and simulations. A joint fit to the νe, νμ, ν¯e, and ν¯μ candidate samples within the 3-flavor neutrino oscillation framework continues to yield a best-fit point in the normal mass ordering and the upper octant of the θ23 mixing angle, with Δm2 32 ¼ ð2.41 0.07Þ × 10−3 eV2 and sin2 θ23 ¼ 0.57þ0.03 −0.04 . The data disfavor combinations of oscillation parameters that give rise to a large asymmetry in the rates of νe and ν¯e appearance. This includes values of the charge parity symmetry (CP) violating phase in the vicinity of δCP ¼ π=2 which are excluded by > 3σ for the inverted mass ordering, and values around δCP ¼ 3π=2 in the normal ordering which are disfavored at 2σ confidence.