Cell elongation by the cytokinetic machinery--Pinching without dividing
Loganathan, Rajprasad
Loganathan, Rajprasad
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2014-05
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Article
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Cell elongation,Notochord,Morphogenesis,Actomyosin
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Loganathan, R. (2014). Cell elongation by the cytokinetic machinery--Pinching without dividing. Journal of Postdoctoral Research, 2(5), 45-47. https://www.postdocjournal.com/archives/715/cell-elongation-by-the-cytokinetic-machinery-%E2%80%93-pinching-without-dividing.htm
Abstract
Cell elongation is an integral component of cell shape changes that occur during morphogenesis of tissues and organs during embryogenesis. A common morphogenetic process accomplishes tissue elongation through intercalation of proliferating cells. Meanwhile, tissues could also elongate as a result of elongation of the constituent cells. A recent study by Sehring et al., identifies a role for the cytokinetic machinery of non-dividing cells in tissue elongation. Focal actomyosin at the cell equator, similar to the apparatus used during cytokinesis, drives this cell-scale elongation. It is possible that the strategy outlined in this study for cell elongation is utilized by a variety of cell types, in various developmental contexts, to direct cell elongation and consequently tissue/organ elongation.
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Featured as a "Research Highlight in Developmental Biology" in the Journal of Postdoctoral Research.
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PostDoc Journal, Journal of Postdoctoral Research
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2328-9791