Loading...
Broad-spectrum antivirals against 3C or 3C-like proteases of picornavirus-like supercluster: Picornaviruses, caliciviruses and coronaviruses
Chang, Kyeong-Ok Kim, Yunjeong Groutas, William C. Hua, Duy H. Saif, Linda J.
Chang, Kyeong-Ok
Kim, Yunjeong
Groutas, William C.
Hua, Duy H.
Saif, Linda J.
Files
Loading...
WO/2013/049382
Adobe PDF, 4.15 MB
Location
Time Period
Advisors
Original Date
Digitization Date
Issue Date
2013-04-04
Type
Patent
Genre
Keywords
Subjects (LCSH)
Citation
Chang, K., Kim, Y., Groutas, W.C., Hua, D.H., Saif, L.J., inventors; Wichita State University, Kansas State University Research Foundation, The Ohio State University, assignees. Broad-spectrum antivirals against 3C or 3C-like proteases of picornavirus-like supercluster: Picornaviruses, caliciviruses and coronaviruses. World Intellectual Property Organization WO/2013/049382. 2013, April 4.
Abstract
Antiviral protease inhibitors, including peptidyl aldehydes, peptidyl ?-ketoamides, peptidyl bisulfite salts, and peptidyl heterocycles, are disclosed, along with related antiviral compounds, and methods of using the same to treat or prevent viral infection and disease. The compounds possess broad-spectrum activity against viruses that belong to the picornavirus-like supercluster, which include important human and animal pathogens including noroviruses, enteroviruses, poliovirus, foot-and-mouth disease virus, hepatitis A virus, human rhinovirus (cause of common cold), human coronavirus (another cause of common cold), transmissible gastroenteritis virus, murine hepatitis virus, feline infectious peritonitis virus, and severe acute respiratory syndrome coronavirus.
Table of Contents
Description
WSU inventor: Groutas, William C., Dept. of Chemistry, College of Liberal Arts and Sciences
International Application No: PCT/US2012/057609 filed September 27, 2012. Patent No: WO/2013/049382 granted April 4, 2013.
International Application No: PCT/US2012/057609 filed September 27, 2012. Patent No: WO/2013/049382 granted April 4, 2013.
Publisher
World Intellectual Property Organization
Journal
Book Title
Series
Digital Collection
Finding Aid URL
Use and Reproduction
Status: Publication 2013-04-04