Nursing home residents often have a sedentary lifestyle. We have previously reported that frail older women residing in a nursing home experience a significant progressive loss of muscle mass. In addition, many nursing home residents have limitations in performing active exercises, especially weight-bearing exercises, due to orthopedic conditions, musculoskeletal conditions, excess adiposity, poor balance, and/or age-associated sarcopenia. The purpose of this study was to determine the effects of a 12-month program consisting of marching in place and chair rising exercise on ADL and function in nursing home residents.