Sweat is an important bodily fluid that can be non-invasively collected from many different areas of the body and contains valuable biomarkers for a variety of clinical and physiological applications, including early diagnosis of diseases. Current sweat analysis relies on sweat samples collected using absorbent pads or rigid tubes, which are inconvenient and not suitable for continuous, real-time monitoring. Therefore, this study seeks to create a sweat monitoring system that can offer continuous, wireless sweat analysis while maintaining user comfort. The goal of this study will be achieved by focusing on three specific aims: 1) the development of solid-state miniaturized electrochemical sensors for pH, sodium and glucose, 2) the optimization of Near Field Communication (NFC) antennas with longer working distances, and 3) the integration of components onto a low-profile, skin-wearable platform. To accomplish the first aim, various sensors have been developed and fabricated to optimize performance and longevity. Testing is currently being carried out to experimentally determine thresholds and values that relate to physiological levels of pertinent biomarkers. The second aim is being researched by designing, fabricating, and testing antennas with varied parameters. The resonant frequency and working distance of the antennas are being analyzed to determine which parameters allow for optimal performance that will yield smooth and easy wireless transmission of data. Once this research has been completed, the focus will shift to developing a low-profile, user-friendly housing unit for the various components. This will be followed by experimentation to ensure optimal and accurate performance of the sweat-monitoring device.