Optimization approaches to volumetric modulated arc therapy planning
Unkelbach, Jan Bortfeld, Thomas Craft, David Alber, Markus Bangert, Mark Bokrantz, Rasmus Chen, Danny Li, Ruijiang Xing, Lei Men, Chunhua
Unkelbach, Jan
Bortfeld, Thomas
Craft, David
Alber, Markus
Bangert, Mark
Bokrantz, Rasmus
Chen, Danny
Li, Ruijiang
Xing, Lei
Men, Chunhua
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2015-03
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Article
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Keywords
Radiotherapy,Treatment plan optimization,VMAT
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Citation
Unkelbach, Jan; Bortfeld, Thomas; Craft, David; Alber, Markus; Bangert, Mark; Bokrantz, Rasmus; Chen, Danny; Li, Ruijiang; Xing, Lei; Men, Chunhua; Nill, Simeon; Papp, David; Romeijn, Edwin; Salari, Ehsan. 2015. Optimization approaches to volumetric modulated arc therapy planning. Medical Physics, vol. 42:no. 3:pp 1367-1377
Abstract
Volumetric modulated arc therapy (VMAT) has found widespread clinical application in recent years. A large number of treatment planning studies have evaluated the potential for VMAT for different disease sites based on the currently available commercial implementations of VMAT planning. In contrast, literature on the underlying mathematical optimization methods used in treatment planning is scarce. VMAT planning represents a challenging large scale optimization problem. In contrast to fluence map optimization in intensity-modulated radiotherapy planning for static beams, VMAT planning represents a nonconvex optimization problem. In this paper, the authors review the state-of-the-art in VMAT planning from an algorithmic perspective. Different approaches to VMAT optimization, including arc sequencing methods, extensions of direct aperture optimization, and direct optimization of leaf trajectories are reviewed. Their advantages and limitations are outlined and recommendations for improvements are discussed.
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American Association of Physicists in Medicine
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Medical Physics;v.42:no.3
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0094-2405