Optimization approaches to volumetric modulated arc therapy planning

No Thumbnail Available
Authors
Unkelbach, Jan
Bortfeld, Thomas
Craft, David
Alber, Markus
Bangert, Mark
Bokrantz, Rasmus
Chen, Danny
Li, Ruijiang
Xing, Lei
Men, Chunhua
Issue Date
2015-03
Type
Article
Language
en_US
Keywords
Radiotherapy , Treatment plan optimization , VMAT
Research Projects
Organizational Units
Journal Issue
Alternative Title
Abstract

Volumetric modulated arc therapy (VMAT) has found widespread clinical application in recent years. A large number of treatment planning studies have evaluated the potential for VMAT for different disease sites based on the currently available commercial implementations of VMAT planning. In contrast, literature on the underlying mathematical optimization methods used in treatment planning is scarce. VMAT planning represents a challenging large scale optimization problem. In contrast to fluence map optimization in intensity-modulated radiotherapy planning for static beams, VMAT planning represents a nonconvex optimization problem. In this paper, the authors review the state-of-the-art in VMAT planning from an algorithmic perspective. Different approaches to VMAT optimization, including arc sequencing methods, extensions of direct aperture optimization, and direct optimization of leaf trajectories are reviewed. Their advantages and limitations are outlined and recommendations for improvements are discussed.

Description
Click on the DOI link to access the article (may not be free).
Citation
Unkelbach, Jan; Bortfeld, Thomas; Craft, David; Alber, Markus; Bangert, Mark; Bokrantz, Rasmus; Chen, Danny; Li, Ruijiang; Xing, Lei; Men, Chunhua; Nill, Simeon; Papp, David; Romeijn, Edwin; Salari, Ehsan. 2015. Optimization approaches to volumetric modulated arc therapy planning. Medical Physics, vol. 42:no. 3:pp 1367-1377
Publisher
American Association of Physicists in Medicine
License
Journal
Volume
Issue
PubMed ID
DOI
ISSN
0094-2405
EISSN