Hybrid polymeric-metallic foams for bone tissue engineering scaffolds: Mechanical properties and biofunctionality evaluations

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Authors
Mahapatro, Anil
Hlaing, Hay Mar
Malladi, Lipi
Keshavanarayana, Suresh R.
Advisors
Issue Date
2021-10-21
Type
Article
Keywords
Polymer foams , Scaffolds , Bone tissue engineering , Biocompatibility
Research Projects
Organizational Units
Journal Issue
Citation
Mahapatro, A., Hlaing, H. M., Malladi, L., & Keshavanarayana, S. (2021). Hybrid polymeric-metallic foams for bone tissue engineering scaffolds: Mechanical properties and biofunctionality evaluations. International Journal of Polymeric Materials and Polymeric Biomaterials, doi:10.1080/00914037.2021.1990058
Abstract

Challenges exist in the applicability of thermoplastic foams as scaffolds for bone tissue engineering including mismatch of mechanical properties. Template assisted electrodeposition was carried out to fabricate hybrid polymeric-metallic foams. Compression test, cytotoxicity and biofunctionality evaluations was performed on polyurethane coated niobium foams to investigate the enhancement of desired properties. Results indicated that ultimate compressive strength of polyurethane foams improved due to the niobium coatings. Biocompatibility evaluations showed that the niobium coated foams were biocompatible. Bio-functionality evaluations showed that the coating of niobium on polyurethane decreases its ability to support osteoblastic cell attachment and proliferation.

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Publisher
Taylor and Francis
Journal
Book Title
Series
International Journal of Polymeric Materials and Polymeric Biomaterials;
PubMed ID
DOI
ISSN
0091-4037
1563-535X
EISSN