Activities of daily living (ADLs) are a crucial part of a person's everyday life. When the ability to complete these tasks is compromised by fatigue due to a cardiovascular condition, does a person's quality of life diminish? A poor Health Related Quality of Life (HRQoL) score has been correlated to older individuals with a cardiovascular condition and puts them at a higher risk of rehospitalization thus lowering their overall QoL. Research reveals that rehab services provided by occupational therapists demonstrate a lack of patient education on proper energy conservation to their patients with heart disease creating a concern that rehab providers are not 1doing enough for the well-being of our patients to help them to remain independent in their ADLs. There is evidence showing individuals with certain cardiovascular diseases suffer from fatigue if they have various biological, psychological, and social determinants such as older age, other comorbidities, diagnosed depression, and marital status. However, there is a lack of evidence that shows how fatigue affects a person's quality of life (QoL), or how physical therapists are addressing fatigue in this patient population. PURPOSE: The purpose of our study is to see if adults who live with a cardiovascular disease suffer from fatigue and how it affects their quality of life as compared to those who do not suffer from fatigue. Our findings will lead us to recommend further studies regarding the relationship between fatigue and QoL in patients with cardiovascular disease and how this should be assessed as physical therapists in order to provide the best interventions and patient education when working with a patient diagnosed with a cardiovascular disease. METHODS: Participants with cardiovascular disease were recruited from Wichita State University and various community facilities via flyers, emails, word of mouth, and social media posts. Each research volunteer was asked to answer demographic questions and complete 2 surveys, the World Health Organization Quality of Life BREF (WHOQOL-BREF) Scale and the Fatigue Assessment Scale (FAS). A correlation coefficient was used to identify if there was a significant relationship between scores on the FAS and scores on the WHOQOL-BREF in participants with self-reported cardiovascular disease. RESULTS: Forty-one qualifying participants completed the two surveys. Significant and inverse relationships were found between the FAS scores and scores on each of the subscales of the WHOQOLBREF. The Pearson Correlation showed a value of p=-0.545 between the sum of FAS and the general health of the participant (p=-0.545). Therefore, a significant correlation was found between the fatigue reported by the participant and their perceived QoL. CONCLUSION: Clinically, physical therapists have the ability to contribute to patient quality of life with a variety of interventions. This may include energy conservation techniques and interval exercise training, which can be utilized for patients suffering from fatigue. Following our data analysis, we found that participants that reported higher fatigue scores generally reported lower QoL scores, suggesting that physical therapists should screen for fatigue in their patients with cardiovascular disease.