Indiana Jones is one of the most iconic figures of the last century. The impact of Jones films on the film industry and popular culture may be inestimable. Despite this fact, few thematic analyses of the Indiana Jones franchise have been completed. At the same time, the dialogue between science and religion is one of the most controversial and important topics in modern society. Yet only a few formal studies have considered how this dialogue between science and religion is portrayed in popular film. The results of a thematic analysis of the Indiana Jones films suggest that popular culture, specifically films, are a viable medium for discussing issues like science and religion.