Design, synthesis and biological evaluation of succinimide derivatives as potential mechanism-based inhibitors of human leukocyte elastase, cathepsin G and proteinase 3

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Authors
Groutas, William C.
Brubaker, Michael J.
Chong, Lee S.
Venkataraman, Radhika
Huang, He
Epp, Jeffrey B.
Kuang, Rongze
Hoidal, John R.
Issue Date
1995-04-01
Type
Article
Language
eng
Keywords
Research Support, Non-U.S. Gov't , Research Support, U.S. Gov't, P.H.S.
Research Projects
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Alternative Title
Abstract

Structure-activity relationship study and in vitro biochemical studies with human leukocyte elastase, cathepsin G and proteinase 3 were conducted using a series of succinimide derivatives.

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Full text of this article is not available in SOAR.
Citation
Bioorganic & medicinal chemistry. 1995 Apr; 3(4): 375-81.
Publisher
Elsevier
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Journal
Volume
Issue
PubMed ID
DOI
ISSN
0968-0896
EISSN