Macrocyclic and peptidomimetic compounds as broad-spectrum antivirals against 3C or 3C-like proteases of picornaviruses, caliciviruses and coronaviruses

Loading...
Thumbnail Image
Authors
Chang, Kyeong-Ok
Kim, Yunjeong
Groutas, William C.
Issue Date
2015-03-11
Type
Patent
Language
Keywords
Research Projects
Organizational Units
Journal Issue
Alternative Title
Abstract

Abstract not available for EP2844249A1 - abstract of corresponding document: WO2013166319A1 Antiviral protease inhibitors, including macrocylic transition state inhibitors and peptidomimetics are disclosed, along with related antiviral compounds, and methods of using the same to treat or prevent viral infection and disease. The compounds possess broad-spectrum activity against viruses that belong to the picornavirus-like supercluster, which include important human and animal pathogens including noroviruses, sapoviruses, enteroviruses, poliovirus, foot-and-mouth disease virus, hepatitis A virus, human rhinovirus (cause of common cold), human coronavirus (another cause of common cold), transmissible gastroenteritis virus, murine hepatitis virus, feline infectious peritonitis virus, and severe acute respiratory syndrome coronavirus.

Description
WSU inventor: William C. Groutas, Dept. of Chemistry, College of Liberal Arts and Sciences
Application No: EP13784550A filed May 2, 2013. Patent No: EP2844249A1 granted March 11, 2015.
Citation
Chang, K., Kim, Y., Groutas, W.C., inventors; Kansas State University Research Foundation, Wichita State University, assignees. Macrocyclic and peptidomimetic compounds as broad-spectrum antivirals against 3C or 3C-like proteases of picornaviruses, caliciviruses and coronaviruses. European Patent Office EP2844249A1. 2015, March 11.
Publisher
European Patent Office
License
Status: Withdrawn
Journal
Volume
Issue
PubMed ID
DOI
ISSN
EISSN