Purpose: This study applies organizational information processing theory (OIPT) to investigate managing production process variability in uncertain environments using information technology (IT) capabilities. Design/methodology/approach: We conduct an empirical analysis using the three-stage least squares (3SLS) technique on 1,612 manufacturing firms over ten years. Findings: The findings show that IT capability plays a dual role: it reduces the positive impact of environmental uncertainty on production process variability and mitigates the negative relationship between production process variability and operational performance. Practical implications: Our findings suggest that managers should focus on reducing production process variability by strengthening their firms' IT capabilities. This is particularly crucial in volatile environments where external uncertainties can significantly impact operational processes. Originality/value: Variability in the production process is a significant source of inefficiency and disruption within business processes. Using OIPT, our study contributes to the field by empirically analyzing the role of IT capabilities in reducing production process variability under environmental uncertainty. © 2024, Emerald Publishing Limited.