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Human chymase inhibitors based on the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold

Groutas, William C.
Schechter, Norman M.
He, Shu
Yu, Hongyi
Huang, Peng
Tu, Juan
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1999-08-02
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Article
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Keywords
Research Support, Non-U.S. Gov't,Research Support, U.S. Gov't, P.H.S.
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Research Projects
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Journal Issue
Citation
Bioorganic & medicinal chemistry letters. 1999 Aug 2; 9(15): 2199-204.
Abstract
A series of compounds that utilize the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold was synthesized and shown to be highly effective inhibitors of recombinant human skin chymase.
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Publisher
Elsevier
Journal
Bioorganic and Medicinal Chemistry Letters
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NLM
PubMed ID
DOI
ISSN
0960-894X
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