The present study was designed to determine whether significant differences existed in typical adults in the preferences across two symbol sets (Boardmaker® or Overboard®) frequently displayed on the augmentative and alternative communication (AAC) systems. Three research questions were addressed. Is one symbol set more preferable than the other for typical adults? Is one symbol set preferred over the other by age groups? What qualitative data can be found to validate symbol preferences? A total of 56 participants participated in the study. Three tasks were involved in the study. The results indicated that regardless of the category (i.e., nouns, verbs, descriptors), the Boardmaker® symbol set is most preferred among the most typical participants except the age of 51-60, but did not reach the significant difference statistically.