Minimizing hypoglycemia in diabetes
Amiel, Stephanie A. Aschner, Pablo Childs, Belinda P. Cryer, Philip E. de Galan, Bastiaan Heller, Simon R. Frier, Brian M. Gonder-Frederick, Linda Jones, Timothy Khunti, Kamlesh
Amiel, Stephanie A.
Aschner, Pablo
Childs, Belinda P.
Cryer, Philip E.
de Galan, Bastiaan
Heller, Simon R.
Frier, Brian M.
Gonder-Frederick, Linda
Jones, Timothy
Khunti, Kamlesh
Other Names
Location
Time Period
Advisors
Original Date
Digitization Date
Issue Date
2015-08
Type
Article
Genre
Keywords
Subcutaneous insulin infusion,Multiple daily injections,Randomized controlled-trials,All-cause mortality,Glycemic control,Glucose control,Cardiovascular diseases,Structured education,Cardiac-arrhythmias,Impaired awareness
Subjects (LCSH)
Citation
Amiel, Stephanie A.; Aschner, Pablo; Childs, Belinda P.; Cryer, Philip E.; de Galan, Bastiaan; Heller, Simon R.; Frier, Brian M.; Gonder-Frederick, Linda; Jones, Timothy; Khunti, Kamlesh; Leiter, Lawrence A.; Luo, Yingying; Vigersky, Robert; Zoungas, Sophia. 2015. Minimizing hypoglycemia in diabetes. Diabetes Care, August 2015:vol. 38:no. 8:pp 1583-1591
Abstract
Hypoglycemia caused by treatment with a sulfonylurea, a glinide, or insulin coupled with compromised defenses against the resulting falling plasma glucose concentrations is a problem for many people with diabetes. It is often recurrent, causes significant morbidity and occasional mortality, limits maintenance of euglycemia, and impairs physiological and behavioral defenses against subsequent hypoglycemia. Minimizing hypoglycemia includes acknowledging the problem; considering each risk factor; and applying the principles of intensive glycemic therapy, including drug selection and selective application of diabetes treatment technologies. For diabetes health-care providers treating most people with diabetes who are at risk for or are suffering from iatrogenic hypoglycemia, these principles include selecting appropriate individualized glycemic goals and providing structured patient education to reduce the incidence of hypoglycemia. This is typically combined with short-term scrupulous avoidance of hypoglycemia, which often will reverse impaired awareness of hypoglycemia. Clearly, the risk of hypoglycemia is modifiable.
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Publisher
American Diabetes Association
Journal
Book Title
Series
Diabetes Care;v.38:no.8
Digital Collection
Finding Aid URL
Use and Reproduction
Archival Collection
PubMed ID
DOI
ISSN
0149-5992