Systematic data integration platform for functional glycomics

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Authors
Visvanathan, Mahesh
Siddam, Sasidhar R.
Lee, In-Hee
Lushington, Gerald H.
Bousfield, George R.
Issue Date
2010
Type
Conference paper
Language
en_US
Keywords
Functional glycomics , Web-based data management system , Mass spectrometry data , Glycan structure
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Abstract

Glycomics is a discipline of biology that deals with the structure and function of glycans (or carbohydrates). Analytical techniques such as mass spectrometry (MS) and nuclear magnetic resonance (NMR) are having a significant impact on the field of glycomics. However, effective progress in glycomics research requires collaboration between laboratories to share experimental data, structural information of glycans, and simulation results. Herein we report the development of a web-based data management system that can incorporate large volumes of data from disparate sources and organize them into a uniform format for users to store and access. This system enables participating laboratories to set up a shared data repository which members of interdisciplinary teams can access. The system is able to manage and share raw MS data and structural information of glycans. The web-based interface will be available at http://www.glycomics.bcf.ku.edu/ (public release projected for xx/xx/2010).

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Mahesh Visvanathan, Sasidhar R. Siddam, In-Hee Lee, Gerald H. Lushington, George R. Bousfield; Systematic data integration platform for functional glycomics; BCB '10 Proceedings of the First ACM International Conference on Bioinformatics and Computational Biology Pages 435-438 ACM New York, NY, USA ©2010; ISBN: 978-1-4503-0438-2; doi:10.1145/1854776.1854848
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AMC
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978-1-4503-0438-2
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