INTRODUCTION: Whole-body vibration (WBV) has been shown to increase muscle fiber recruitment during isotonic contractions. No prior published studies have used elastic resistance. PURPOSE: The main purpose of this study is to investigate the acute effects of a single bout of WBV on electromyography (EMG) activity during exercise when using elastic resistance. METHOD: 30 participants (14 male; 16 female) aged 18-30 were recruited for this study. EMG activity was then determined while participants performed the arm curl and squats using elastic resistance under three conditions: no vibration exposure, during acute vibration exposure, and following acute vibration exposure. Three upper extremity muscles were monitored during the arm curl. Vibration was administered using a vibration platform (Wave®; ProElite, Windsor, ON Canada) at a frequency of 35Hz at 4mm displacement amplitude. RESULTS: Results indicate no statistically significant differences between the three conditions for the upper body but there was a decrease in the primary muscles involved in the concentric phase of the squat immediately after vibration exposure. CONCLUSION: These results suggest that there may be an effect of vibration on muscles in the lower body following vibration.