The movement of actin–myosin biomolecular linear motor under AC electric fields: An experimental study
Lee, Yongkuk Famouri, Parviz
Lee, Yongkuk
Famouri, Parviz
Authors
Other Names
Location
Time Period
Advisors
Original Date
Digitization Date
Issue Date
2013-03-15
Type
Article
Genre
Keywords
Dielectrophoresis,Electro-orientation,Electrothermal effect,AC electric field,Myosin,Actin filament
Subjects (LCSH)
Citation
Lee, Y., & Famouri, P. The movement of actin–myosin biomolecular linear motor under AC electric fields: An experimental study, Journal of Colloid and Interface Science, Volume 394, 2013, Pages 312-318, ISSN 0021-9797, https://doi.org/10.1016/j.jcis.2012.11.072.
Abstract
The role of actin–myosin as a biomolecular linear motor is considered a transport system at nanoscale because of their size, efficiency and functionality. To utilize the ability to transport, it is essential to control the random movement of actin filaments (F-actin) on myosin coated substrate. In the presence of an alternating current (AC) electric field, the direction of F-actin movement is regulated by electro-orientation torque and, as a result, its movement is perpendicularly toward the electrode edges. Our data confirm such aligned movement is proportional to the strength of applied electric field. Interestingly, the aligned movement is found frequency-dependent and the electrothermal effect is observed by means of the velocity measurement of aligned F-actin movement. The findings in this study may provide constructive information for manipulating actin–myosin nanotransport system to build functional nanodevices in future work.
Table of Contents
Description
Highlights
► "F-actin movement on HMM coated surface is regulated by electro-orientation torque.
► The aligned movement is proportional to the strength of applied electric field.
► The aligned movement is frequency-dependent.
► The electrothermal effect is observed by means of F-actin velocity measurement."
Publisher
Elsevier
Journal
Journal of Colloid and Interface Science
Book Title
Series
Digital Collection
Finding Aid URL
Use and Reproduction
Archival Collection
PubMed ID
ISSN
0021-9797
1095-7103
1095-7103