The present application draws attention to particulate materials derived from carbonaceous materials, such as carbon foam, as a platform technology for multiple medical procedures performed to address diverse tissue deficits and/or pathologies. The particulates are biocompatible, permissive of cell attachment and differentiation, and provide a 3-dimensional substrate that is permissive of neo-vascularization. Methods are disclosed herein whereby the application and subsequent bodily interactions with the particulate materials with or without composite materials are optimized to provide a technological platform useful for multiple regenerative procedures.