The optimization of delivery plan is a critical issue, especially for multiple perishable products in any profitable organization. This paper develops a model for the efficient implementation of supply chain systems for multiple perishable products. The mathematical model developed maximizes the profit while taking into consideration shelf life and the cost of transportation. The price or value of products is affected by its remaining shelf-life. An optimal delivery plan is developed based on shelf-life, time to transport the perishable products within the network reaching to retailer, while including the minimization of transportation cost in the model. In addition, the optimal delivery plan identifies the right quantity of each type of perishable products to be delivered. In this research, a mathematical model is utilized for solving the multi-objective mathematical problem, which includes revenue maximization, and minimization of transportation models to perform an optimal delivery plan. This paper’s central aim is to maximize the gross profit while identifying the best delivery method for multiple perishable products.