The capability of a computer numerical control (CNC) machine tool equipped with direct computer control coordinate measuring software and high accuracy contact probing is validated for in-situ machine health monitoring and in-situ part quality control. The validation conforms to international standards for performance evaluation of commercially available coordinate measuring machines (CMMs). The capability of the CNC system to perform CMM-type measurements is demonstrated via a case study. The equivalency between part dimensional measurements obtained directly from the use of the CNC machine tool as a CMM and from part dimensional measurements performed using commercially available CMMs is established via a correlation study.