Loading...
Design and synthesizing of hemoglobin-based multifunctional fibers for improved carbon monoxide absorption rates
Pham, Anh Subeshan, Balakrishnan Asmatulu, Eylem Asmatulu, Ramazan
Pham, Anh
Subeshan, Balakrishnan
Asmatulu, Eylem
Asmatulu, Ramazan
Citations
Altmetric:
Other Names
Location
Time Period
Advisors
Original Date
Digitization Date
Issue Date
2025-01-14
Type
Article
Genre
Keywords
Characterization,CO absorption,Electrospinning,Hemoglobin,Multifunction fibers,Testing
Subjects (LCSH)
Citation
Pham, A., Subeshan, B., Asmatulu, E. et al. Design and Synthesizing of Hemoglobin-Based Multifunctional Fibers for Improved Carbon Monoxide Absorption Rates. BioNanoSci. 15, 184 (2025). https://doi.org/10.1007/s12668-025-01807-8
Abstract
This study is aimed at developing advanced materials for carbon monoxide (CO) capture by producing hemoglobin (Hb)-based electrospun multifunctional micro- and nanofibers blended with polyvinylpyrrolidone (PVP). Unlike conventional CO trapping materials such as activated carbon, ammoniacal cuprous chloride, zeolites, and metal-organic frameworks (MOFs), Hb/PVP fibers leverage the simplicity and scalability of electrospinning to produce continuous, defect-free flexible fibers with tunable micron- to nanoscale diameters. The process enables precise control over fiber morphology, surface area, porosity, and hydrophilicity, providing significant advantages for optimizing CO adsorption rates. Moreover, the inclusion of Hb introduces a biomimetic advantage through its intrinsic CO-binding affinity, offering higher specificity and interaction potential compared to traditional physical adsorption or chemical frameworks. Experimental results revealed that fibers with 8 wt.% PVP exhibited the smallest and most uniform diameters, while higher PVP concentrations (16, 32 wt.%) enhanced hydrophilicity, with complete water absorption occurring within 400 and 200 seconds, respectively. Structural and compositional analyses using confocal laser scanning microscopy (CLSM) and Fourier transform infrared spectroscopy (FTIR) confirmed the integrity and chemical characteristics of the fibers. Thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC) established their thermal stability, with critical transitions at approximately 80 ℃ (denaturation) and 200 ℃ (decomposition). Degradation was observed between 200 and 430 ℃, corresponding to significant weight loss. These findings demonstrate the potential of Hb/PVP fibers as exceptional alternatives for CO capture. This study may open new possibilities for increasing the absorption rate of highly porous fibers for toxic CO capture in the bloodstream and address other related concerns. © This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2025.
Table of Contents
Description
This is an open access article under the CC BY license.
Publisher
Springer
Journal
BioNanoScience
Book Title
Series
Digital Collection
Finding Aid URL
Use and Reproduction
Archival Collection
PubMed ID
ISSN
21911630