Gonadotropins and the importance of glycosylation

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Authors
Ulloa-Aguirre, Alfredo
Dias, James A.
Bousfield, George R.
Advisors
Issue Date
2009-09-25
Type
Book chapter
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Research Projects
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Citation
Ulloa-Aguirre, A., Dias, J. A. and Bousfield, G. R. (2009) Gonadotropins and the Importance of Glycosylation, in Post-translational Modification of Protein Biopharmaceuticals (ed G. Walsh), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527626601.ch5
Abstract

From the leading author in the field, known around the world for his work and his authoritative publications, the contents of this book have been selected so as to reflect their relative importance for biopharmaceuticals. As a result, around half of the book is devoted to protein glycosylation, while the remainder is made up of other modifications, such as carboxylation, hydroxylation, sulfation, amidation and proteolytic processing. A final section addresses the latest trend of engineering the modification pattern to improve a given biopharmceutical, presenting several recent case studies of successful posttranslational engineering. This first authoritative overview of the topic is an indispensable guide for drug developers and drug manufacturers with an interest in protein pharmaceuticals.

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Publisher
Wiley-VCH Verlag GmbH & Co. KGaA
Journal
Book Title
Series
Post-translational Modification of Protein Biopharmaceuticals;
;Ch.5
PubMed ID
DOI
ISSN
9783527626601 (Electronic)
EISSN