Neck pain affects between 45% and 54% of the population. The purpose of this study was to compare two different, yet commonly accepted treatments for neck pain. In a randomized trial, 34 subjects were divided into two groups and received joint mobilizations to the thoracic or cervical spine. Outcomes were measured by assessing change in cervical spine range of motion, neck pain as rated on the numeric pain rating system (NPRS), and function as indicated by the Neck Disability Index (NDI) questionnaire. Analysis revealed no significant interaction between cervical and thoracic mobilizations with regard to the NDI, NPRS, or cervical ROM.