Composite magnetic nanoparticle drug delivery system

dc.contributorWichita State University
dc.contributor.authorAsmatulu, Ramazan
dc.contributor.authorMisak, Heath Edward
dc.contributor.authorYang, Shang-You
dc.contributor.authorWooley, Paul H.
dc.date.accessioned2023-07-12T13:17:23Z
dc.date.available2023-07-12T13:17:23Z
dc.date.issued2012-04-19
dc.date.submitted2011-10-11
dc.descriptionWSU inventors: Ramazan Asmatulu, Heath Misak, Dept. of Mechanical Engineering, College of Engineering, Shang-You-Yang, Paul Wooley, Dept. of Biological Sciences, College of Liberal Arts and Sciences
dc.descriptionInternational Application No: PCT/US2011/055847 filed October 11, 2011. Patent No: WO/2012/051220 granted April 19, 2012.
dc.description.abstractA composite magnetic nanoparticle drug delivery system provides targeted controlled release chemotherapies for cancerous tumors and inflammatory diseases. The magnetic nanoparticle includes a biocompatible and biodegradable polymer, a magnetic nanoparticle, the biological targeting agent human serum albumin, and a therapeutic pharmaceutical composition. The composite nanoparticles are prepared by oil-in-oil emulsion/solvent evaporation and high shear mixing. An externally applied magnetic field draws the magnetic nanoparticles to affected areas. The biological targeting agent draws the nanoparticles into the affected tissues. Polymer degradation provides controlled time release delivery of the pharmaceutical agent.
dc.format.extent73 claims; 12 drawings; 51 pages
dc.identifierWO/2012/051220
dc.identifier.citationAsmatulu, R., Misak, H.E., Yang, S., Wooley, P.H., inventors; Wichita State University, assignees. Composite magnetic nanoparticle drug delivery system. World Intellectual Property Organization WO/2012/051220. 2012, April 19.
dc.identifier.urihttps://patentscope.wipo.int/search/en/detail.jsf?docId=WO2012051220
dc.identifier.urihttps://soar.wichita.edu/handle/10057/25560
dc.languageen_US
dc.publisherWorld Intellectual Property Organization
dc.rightsStatus: Publication 2012-04-19
dc.subject.classificationCPI: A61K 9/14 2006.1
dc.subject.classificationCPC: A61K9/0009 A61K9/5031 A61K9/5094 A61P 29/00 A61P 35/00
dc.titleComposite magnetic nanoparticle drug delivery system
dc.typePatent
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