We investigate the curvature operator of the second kind on Riemannian manifolds and prove several classification results. The first one asserts that a closed Riemannian manifold with three-positive curvature operator of the second kind is diffeomorphic to a spherical space form, improving a recent result of Cao?Gursky?Tran assuming two-positivity. The second one states that a closed Riemannian manifold with three-nonnegative curvature operator of the second kind is either diffeomorphic to a spherical space form, or flat, or isometric to a quotient of a compact irreducible symmetric space. This settles the nonnegativity part of Nishikawa?s conjecture under a weaker assumption.