A system and method for generating a channel statistics dependent frequency hopping pattern that requires low computational complexity and simultaneously maximizes channel capacity and minimizes the symbol error rate or bit error rate under partial band tone interference and Rician or other fading environments. The system includes one or more transmitting units and one or more receiving units communicating over a wireless communication network. A signal generated at one of the transmitting units is modified via the channel statistics dependent frequency hopping pattern as generated via one of the receiving units for improved signal accuracy and avoiding interferer detection and/or interference hits.