Four-hundred fifty-eight methadone patients were administered the Symptom Check List-90 (SCL-90). Four profile-shape components were identified by Modal Profile Analysis reflecting (1) Paranoid, (2) Somatic, (3) Hostile, and (4) Anxious-depressed syndromes. Spearman rank-order correlations were then calculated between these four profile-shape components and four same-named ones previously reported for the SCL-90-R with psychiatric patients; the shape components were similar for both instruments. The four shape components were next correlated with the addicts background and treatment characteristics. The paranoid shape was associated with smoking marijuana at a later age and currently using both heroin and marijuana; the somatic shape was related to earlier marijuana use, not being court mandated to treatment, and having current medical problems; the hostile shape was associated with being male, Black, using marijuana at an earlier age, and currently using amphetamines; and the anxious depressed shape was correlated with being Black, not being married, using marijuana at an earlier age, realizing that one had a drug problem at an earlier age, entering drug treatment at an earlier age, and not having a current health problem.