Design and development of hydrogel for effective burn wound healing
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The creation and processing of intelligent hydrogels is becoming more and more of a focus in the field of material science research. As an exterior application, hydrogel compositions are quite successful in managing wound healing. Hydrogels developed for the healing of burn wounds tackle critical issues such controlling moisture, preventing infections, and promoting tissue regeneration. Hydrogels are more therapeutically effective when bioactive substances like growth factors and antibacterial chemicals are included, since this facilitates faster wound closure and tissue healing. Furthermore, regulated medication release and real-time monitoring of wound healing parameters are made possible by improvements in smart hydrogels, enabling customized treatment strategies. Burn wounds continue to be extremely difficult to treat, and burn injuries are a major global health problem. Our goal in this thesis is to create a unique hydrogel that would promote wound healing from burns, lessen pain and inflammation, and stop infections. The primary objective of this study is to investigate the effects of the natural and chemical ingredients in hydrogels recipe on the healing of burn wounds. Hydrogels may be created with customizable characteristics including porosity, swelling behavior, and degradation kinetics by a variety of synthetic techniques, such as physical and chemical cross linking. Hydrogel structure, content and properties may be evaluated by characterization methods including Fourier-transform infrared spectroscopy, Atomic force microscopy, X- ray diffraction, Thermogravimetric analysis and cytotoxicity, which guarantee the hydrogels’ appropriateness for use in burn wound treatments. In conclusion, design and development of hydrogel for effective burn wound healing offers an appropriate way to enhance the standard of care for burn victims and improve results.