Composite magnetic nanoparticle drug delivery system

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Authors
Asmatulu, Ramazan
Misak, Heath
Yang, Shang-you
Wooley, Paul
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Issue Date
2012-10-18
Type
Patent
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Asmatulu, R., Misak, H., Yang, S., & Wooley, P., inventors; Wichita State University, assignee. Composite magnetic nanoparticle drug delivery system. United States patent US 20120265001 A1. 2012, October 18.
Abstract

A composite magnetic nanoparticle drug delivery system pro­vides targeted controlled release chemotherapies for cancer­ous tumors and inflammatory diseases. The magnetic nano­particle includes a biocompatible and biodegradable polymer, a magnetic nanoparticle, the biological targeting agent human serum albumin, and a therapeutic pharmaceuti­cal composition. The composite nanoparticles are prepared by oil-in-oil emulsion/solvent evaporation and high shear mixing. An externally applied magnetic field draws the mag­netic nanoparticles to affected areas. The biological targeting agent draws the nanoparticles into the affected tissues. Poly­mer degradation provides controlled time release delivery of the pharmaceutical agent.

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Description
WSU inventors: Ramazan Asmatulu, Heath Misak, Dept. of Mechanical Engineering, College of Engineering, Shang-you Yang, Dept. of Biology, Fairmount College of Liberal Arts and Sciences
Application No: 13/271,172 filed October 11, 2011. Patent No: US 20120265001 A1 granted October 18, 2012.
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United States Patent and Trademark Office
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