An experimental study was conducted to test the effect of a nurse-client transactional intervention (King, 1981) on 51 female adolescents' oral contraceptive adherence. Subjects were randomly assigned to a control or an experimental group. Both groups experienced the clinics' contraceptive teaching. Subjects in the experimental group experienced the transactional intervention. Contraceptive perceptions were measured immediately post-intervention and at the three-month follow-up. Oral contraceptive adherence was measured at the three-month follow-up. Female adolescents who experienced the transactional intervention had greater levels of oral contraceptive adherence than those who had not (F = 4.15, p < .05).