Exercise-induced benefits in individuals with type 1 diabetes

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Authors
Loganathan, Rajprasad
Searls, Yvonne M.
Smirnova, Irina V.
Stehno-Bittel, Lisa
Advisors
Issue Date
2006
Type
Article
Keywords
Type 1 diabetes , Aerobic exercise , Complications
Research Projects
Organizational Units
Journal Issue
Citation
Loganathan, R., Searls, Y. M., Smirnova, I. V., & Stehno-Bittel, L. (2006). Exercise-induced benefits in individuals with type 1 diabetes. Physical Therapy Reviews, 11(2), 77–89. https://doi.org/10.1179/108331906X99056
Abstract

Individuals with type 1 diabetes are exposed to the pathological effects of chronic hyperglycaemia at an early age. Type 1 diabetes is associated with a variety of complications, including microvascular complications such as diabetic retinopathy, nephropathy, and neuropathy. Conditions like diabetic cardiomyopathy also cause significant mortality and morbidity. The most common macrovascular complications include coronary heart disease, cerebrovascular disease, and peripheral arterial disease. Aerobic exercise is a critical component in the management of individuals with type 1 diabetes. Results from diabetic animal models reveal a variety of cellular mechanisms in response to exercise, producing beneficial effects on diabetic tissue. These results suggest that exercise training leads to improved tissue function by targeting specific adaptive mechanisms in diabetes, especially when initiated at the early stages of the disease. Hence, long-term aerobic exercises produces beneficial effects beyond insulin and nutrition therapy alone, as indicated by epidemiological and clinical studies in type 1 diabetics.

Table of Contents
Description
Issue published: 2006. Article published online: 2013-07-09
Publisher
Taylor & Francis
Journal
Physical Therapy Reviews
Book Title
Series
PubMed ID
ISSN
1743-288X
1083-3196
EISSN