Broad spectrum antivirals against coronavirus

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Authors
Chang, Kyeong-Ok
Kim, Yunjeong
Groutas, William C.
Perlman, Stanley
Advisors
Issue Date
2021-03-30
Type
Patent
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Citation
Chang, K., Kim, Y., Groutas, W.C., & Perlman, S., inventors; Wichita State University, Kansas State University Research Foundation, University Of Iowa Research Foundation, assignees. Broad spectrum antivirals against coronavirus. European Patent Office EP4126816A1. 2023, February 8.
Abstract

Abstract not available for EP4126816A1 - abstract of corresponding document: WO2021202460A1


Compounds exhibiting antiviral activity and/or inhibition of viral replication against viruses, particularly those belonging to the picornavirus-like supercluster, including coronavirus having a formula: (I) where X comprises a cyclic moiety, R is a branched or unbranched alkyl, cycloalkyl, aryl, arylalkyl, alkenyl, alkynyl, amino acid side chain, bicyclic or tricyclic side chain, combinations, and substituted forms thereof, and Z is selected from the group consisting of C-C hydroxyalkyl, aldehydes, alpha- ketoamides, and bisulfite salts, and in particular -CHOH, -CHO, -CH(0H)S0 Na, and - [0(C=0)R]S0 Na.

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Description
WSU inventor: Groutas, William C., Dept. of Chemistry, College of Liberal Arts and Sciences
Application No: EP21781006A filed March 30, 2021. Patent No: EP4126816A1 granted February 8, 2023.
Publisher
European Patent Office
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