Broad-spectrum antivirals against 3C or 3C-like proteases of picornavirus-like supercluster: Picornaviruses, caliciviruses and coronaviruses

Citation

Chang, K., Kim, Y., Groutas, W.C., Hua, D., Saif, L.J., inventors; Kansas State University Research Foundation (Manhattan, KS), The Ohio State University (Columbus, OH), Wichita State University (Wichita, KS), assignees. Broad-spectrum antivirals against 3C or 3C-like proteases of picornavirus-like supercluster: Picornaviruses, caliciviruses and coronaviruses. European Patent Office EP2760827A2. 2014, August 6.

Abstract

Abstract not available for EP2760827A2. Abstract of corresponding document: WO2013049382A2: Antiviral protease inhibitors, including peptidyl aldehydes, peptidyl alpha-ketoamides, peptidyl bisulfite salts, and peptidyl heterocycles, are disclosed, along with related antiviral compounds, and methods of using the same to treat or prevent viral infection and disease. The compounds possess broad-spectrum activity against viruses that belong to the picornavirus-like supercluster, which include important human and animal pathogens including noroviruses, enteroviruses, poliovirus, foot-and-mouth disease virus, hepatitis A virus, human rhinovirus (cause of common cold), human coronavirus (another cause of common cold), transmissible gastroenteritis virus, murine hepatitis virus, feline infectious peritonitis virus, and severe acute respiratory syndrome coronavirus.

Table of Content
Description
WSU inventor: Groutas, William C., Dept. of Chemistry, College of Liberal Arts and Sciences
Application No: EP12837222A filed September 27, 2012. Patent No: EP2760827A2 granted August 6, 2014.
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