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    • LacI-DNA-IPTG loops: Equilibria among conformations by single-molecule FRET 

      Wang, Zifan; Goodson, Kathy A.; Haeusler, Aaron R.; English, Douglas S.; Kahn, Jason D. (Wichita State University. Graduate School., 2012-04-18)
      The E. coli Lac repressor (LacI) tetramer binds simultaneously to a promoter-proximal DNA binding site (operator) and an auxiliary operator, resulting in a DNA loop, which increases repression efficiency. Induction of the ...