Browsing GRASP: Graduate Research and Scholarly Projects by Author "Bann, James G."
Now showing items 1-6 of 6
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$^{19}F$-NMR studies to understand pH induced structural changes in protective antigen anthrax toxin
Gonti, Srinivas; Westler, William M.; Miyagi, Masaru (Wichita State University, 2022-04-29)Anthrax bacteria ($Bacillus$ $anthracis$) produces Protective antigen toxin (PA), Lethal factor (LF) and Edema factor (EF) protein components into the host cells. Protective antigen toxin (PA83 - 83kDa polypeptide) binds ... -
Computational studies on tautomers of fluorinated-histidine and fluorinated-imidazole
Kasireddy, Chandana (Wichita State University. Graduate School, 2014-04-25)Fluorinated amino acids are playing an important role in understanding protein-protein interactions, protein folding and protein structure function. Since histidine contains an imidazole ring, we considered the N1-H and ... -
Dependence of proline isomerization on the kinetics of folding of anthrax lethal factor
Halimeh, Wyel (Wichita State University, 2022-04-29)The death that can come within a few days after exposure to the anthrax toxin from $Bacillus$ $anthracis$ is due to the presence and effects of anthrax lethal factor (LF). LF is a zinc metalloproteinase whose function ... -
Effect of the receptor CMG2 on stability changes in Domain IV of anthrax toxin protective antigen in comparison to the full-length protein
Mamillapalli, Sireesha (Wichita State University, 2016-04-29)The anthrax protective antigen is an 83 kDa protein secreted by Bacillus anthracis, and is required for entry of the edema factor and lethal factor, that leads to Anthrax. PA bound to Capillary Morphogenesis Receptor (CMG2) ... -
F-NMR studies on Anthrax protective antigen -- Restricted access to full text
Chadegani, Fatemeh; Mulangi, Vennela; Miyagi, Masaru; Bann, James G. (Wichita State University. Graduate School., 2012-04-18)Anthrax secretes a three component which is composed of three proteins: lethal factor (LF), edema factor (EF), and protective antigen (PA). PA transfers LF and EF into the host cytosol through a membrane spanning pore, ... -
Generation of a protein based fluorescent reactive oxygen species sensor
Rajapaksha, Maheshinie; Heyen, Bruce J.; Wimalasena, Kandatege; Bann, James G. (Wichita State University. Graduate School., 2007-04-27)The long- term goal of the project is to develop an environmentally safe, sensitive method for the detection of reactive oxygen species. The current hypothesis is that the biosynthetic incorporation of [2,5-H2]-phenylalanine ...