• Evolution of stability/flexibility relationships in beta-lactamase 

  Patterson, John; Tsilimigras, Matthew C. B.; Livesay, Dennis R.; Jacobs, Donald J. (Cell Press, 2019-02-15)

  We have curated over 100 structures of class A beta-lactamase proteins, a family of enzymes that is responsible for a considerable percentage of multidrug antibiotic resistance in bacteria. Our dataset includes three ...

• Characterizing dynamical differences between TEM-1 and TEM-52 beta-lactamases 

  Avery, Christopher; Farmer, Jenny; Tsilimigras, Matthew C. B.; David, Charles; Livesay, Dennis R.; Jacobs, Donald J. (Cell Press, 2019-02-15)

  Beta-lactamase, produced in bacteria, defends against beta-lactam antibiotics such as penicillin and cephalosporins by hydrolyzing the beta-lactam ring. This is a primary cause of antibiotic resistance to beta-lactam ...

• Material characterization and bioanalysis of hybrid scaffolds of carbon nanomaterial and polymer nanofibers 

  Srikanth, Madhulika; Asmatulu, Ramazan; Cluff, Kim; Yao, Li (ACS, 2019-03-08)

  The interconnected porous structures that mimic the extracellular matrix support cell growth in tissue engineering. Nanofibers generated by electrospinning can act as a vehicle for therapeutic cell delivery to a neural ...

• Ultrahigh conductivity and superior interfacial adhesion of a nanostructured, photonic-sintered copper membrane for printed flexible hybrid electronics 

  Kwon, Young-Tae; Kim, Yun-Soung; Lee, Yongkuk; Kwon, Shinjae; Lim, Minseob; Song, Yoseb; Choa, Yong-Ho; Yeo, Woon-Hong (American Chemical Society, 2018-11-19)

  Inkjet-printed electronics using metal particles typically lack electrical conductivity and interfacial adhesion with an underlying substrate. To address the inherent issues of printed materials, this Research Article ...

• Migration through a small pore disrupts inactive chromatin organization in neutrophil-like cells 

  Jacobson, Elsie C.; Perry, Jo K.; Long, David S.; Olins, Ada L.; Olins, Donald E.; Wright, Bryon E.; Vickers, Mark H.; O'Sullivan, Justin M. (BioMed Central Ltd., 2018-11-26)

  Background. Mammalian cells are flexible and can rapidly change shape when they contract, adhere, or migrate. The nucleus must be stiff enough to withstand cytoskeletal forces, but flexible enough to remodel as the cell ...

• Passive self resonant skin patch sensor to monitor cardiac intraventricular stroke volume using electromagnetic properties of blood 

  Alruwaili, Fayez H.; Cluff, Kim; Griffith, Jacob L.; Farhoud, Hussam (IEEE, 2018-09-26)

  This paper focuses on the development of a passive, lightweight skin patch sensor that can measure fluid volume changes in the heart in a non-invasive, point-of-care setting. The wearable sensor is an electromagnetic, ...

• The effects of a fatiguing lifting task on postural sway among males and females 

  Bannon, Helen; Hakansson, Nils A.; Jakobsen, Markus D.; Sundstrup, Emil; Jorgensen, Michael J. (Elsevier, 2018-06)

  Lifting and falls comprise a large proportion of work related injuries. Repetitive lifting to the point of fatigue can affect postural sway, which is associated with fall risk. To investigate the effects of lifting and ...

• Non-invasive electromagnetic skin patch sensor to measure intracranial fluid–volume shifts 

  Griffith, Jacob; Cluff, Kim; Eckerman, Brandon; Aldrich, Jessica; Becker, Ryan; Moore-Jansen, Peer; Patterson, Jeremy (MDPI, Basel, Switzerland, 2018-03-29)

  Elevated intracranial fluid volume can drive intracranial pressure increases, which can potentially result in numerous neurological complications or death. This study’s focus was to develop a passive skin patch sensor for ...

• Fabrication of magnesium-based metallic scaffolds for bone tissue engineering 

  Malladi, Lipi; Mahapatro, Anil; Gomes, Anosh Steffin (Taylor & Francis, 2018)

  Repairing and regenerating defects of large bones caused by disease or trauma is a significant clinical challenge. Extensive research has been done on bone tissue regeneration incorporating biodegradable scaffolds mainly ...

• Editorial: Metallic biomaterials 

  Mahapatro, Anil (Taylor & Francis, 2018)

  Metals in biomedical devices are exploited due to their inertness and structural functions. Several opportunities exist for implantable metallic biomaterials to enhance the bio functionality of current metallic biomaterials ...

• Preliminary validation of a dynamic electrochemical biodegradation test bench in pseudo-physiological conditions 

  Gayle, J.; Mahapatro, Anil; Lundin, H. (Taylor & Francis, 2018)

  There is a growing interest in the development of next-generation stent materials. In vitro tests that accurately predict in vivo conditions are desired. In this manuscript, a novel approach for the design of a dynamic ...

• Passive wearable skin patch sensor measures limb hemodynamics based on electromagnetic resonance 

  Cluff, Kim; Becker, Ryan A.; Jayakumar, Balakumar; Han, Kiyun; Condon, Ernie; Dudley, Kenneth; Szatkowski, George; Pipinos, Iraklis I.; Amick, Ryan Zackary; Patterson, Jeremy A. (IEEE, 2018-04)

  Objective: The objectives of this study were to design and develop an open-circuit electromagnetic resonant skin patch sensor, characterize the fluid volume and resonant frequency relationship, and investigate the sensor's ...

• Concurrent validity of heart rate measures using a wrist worn activity tracker during treadmill walking 

  Shargawi, Anas A.; Hafez, Khaled A. (Wichita State University, 2018-04-27)

  Introduction: Wearable technology devices are becoming increasingly popular. Many of these devices offer features allowing users to monitor health related biometric information. One biometric variable commonly measured is ...

• Electro-poroelastohydrodynamics of the endothelial glycocalyx layer 

  Sumets, P. P.; Cater, J. E.; Long, David S.; Clarke, R. J. (Cambridge University Press, 2018-03-10)

  We consider pressure-driven flow of an ion-carrying viscous Newtonian fluid through a non-uniformly shaped channel coated with a charged deformable porous layer, as a model for blood flow through microvessels that are lined ...

• Analysis of ischemic muscle in patients with peripheral artery disease using X-ray spectroscopy 

  Becker, Ryan A.; Cluff, Kim; Duraisamy, Nithyanandhi; Casale, George P.; Pipinos, Iraklis I. (Elsevier, 2017-12)

  Background: Peripheral artery disease (PAD) is a vascular disease caused by atherosclerosis, resulting in decreased blood flow to the lower extremities. The ankle-brachial index (ABI) is a standard PAD diagnostic test but ...

• Non-invasive point-of-care method for measuring left-ventricular stroke-volume using a passive electromagnetic skin patch sensor 

  Alruwaili, Fayez H.; Griffith, Jacob L.; Cluff, Kim; Patterson, Jeremy A. (Elsevier Inc., 2017-03-21)

  The aim of this study was to develop a non-invasive mobile skin patch sensor – applied like an adhesive bandage which could potentially measure left-ventricular stroke volume (LVSV).

• Non-invasive biomedical patch sensor to measure intracranial pressure 

  Griffith, Jacob L.; Wakim, Andre A.; Moore-Jansen, Peer H.; Cluff, Kim (IEEE, 2016)

  This study was focused on the development of a non-invasive mobile skin sensor for measuring intracranial pressure (ICP). Current techniques are limited to surgical implantations or methods that require highly specialized ...

• Nanostructured self assembled monolayers on magnesium for improved biological performance 

  Mahapatro, Anil; Negron, Taina D. Matos; Gomes, Anosh (Taylor & Francis LTD, 2016)

  Magnesium (Mg) and its alloys are being extensively investigated for its use as a biodegradable metallic implant material. Surface modification strategies are critical for Mg to be able to address application-specific ...

• An evaluation of the state of neuromuscular blockade monitoring devices 

  Hund, Hannah Christine; Rice, Mark John; Ehrenfeld, Jesse (Springer International Publishing, 2016-12)

  A core element of anesthesia care is the use of intravenous muscle relaxants. While neuromuscular blockade (NMB) monitoring devices assess the degree of patient paralysis, few clinically convenient monitors exist. The lack ...

• Determination of yolk contamination in liquid egg white using Raman spectroscopy 

  Cluff, Kim; Naganathan, Govindarajan Konda; Jonnalagada, D.; Mortensen, I.; Wehling, R.; Subbiah, J. (Oxford University Press, 2016-07)

  Purified egg white is an important ingredient in a number of baked and confectionary foods because of its foaming properties. However, yolk contamination in amounts as low as 0.01% can impede the foaming ability of egg ...

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