Browsing Fairmount College of Liberal Arts and Sciences by Type "Article"
Now showing items 1-20 of 2034
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1,2,5-Thiadiazolidin-3-one 1,1 dioxide: a powerful scaffold for probing the S' subsites of (chymo)trypsin-like serine proteases
(Elsevier, 2001-01-01)The 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold (I) embodies a motif that allows it to dock to the active site of (chymo)trypsin-like proteases in a predictable and substrate-like fashion. Consequently, inhibitors ... -
1,2,5-Thiadiazolidin-3-one 1,1-dioxide-based heterocyclic sulfides are potent inhibitors of human tryptase
(Elsevier, 2005-04-01)We describe herein the design, synthesis, and in vitro biochemical evaluation of a series of potent, time-dependent inhibitors of the mast cell-derived serine protease tryptase. The inhibitors were readily obtained by ... -
158 Production of recombinant LH for use in tiger ( tigris altaica ) assisted reproduction: a preliminary report
(CSIRO, 2007-12-12)Genetically, porcine LH is the closest commercially available gonadotropin analog to tiger LH (93% homologous); however, its use may lead to possible autoimmune reactions, lessening ovarian responses in stimulated tigresses ... -
19F nuclear magnetic resonance and crystallographic studies of 5-fluorotryptophan-labeled anthrax protective antigen and effects of the receptor on stability
(American Chemical Society, 2014-02-04)The anthrax protective antigen (PA) is an 83 kDa protein that is one of three protein components of the anthrax toxin, an AB toxin secreted by Bacillus anthracis. PA is capable of undergoing several structural changes, ... -
2, 2'-and 4, 4'-Cyanines are transporter-independent in vitro dopaminergic toxins with the specificity and mechanism of toxicity similar to MPP+
(Wiley Periodicals, Inc., 2015-11)Specific uptake through dopamine transporter followed by the inhibition of the mitochondrial complex-I have been accepted as the cause of the specific dopaminergic toxicity of 1-methyl-4-phenylpyridinium (MPP+). However, ... -
2-Fluoro-l-histidine
(International Union of Crystallography, 2010-01-01)The title compound, C(6)H(8)FN(3)O(2), an analog of histidine, shows a reduced side-chain pK(a) (ca 1). The title structure exhibits a shortening of the bond between the proximal ring N atom and the F-substituted ring C ... -
3-(Alkylthio)-N-hydroxysuccinimide derivatives: potent inhibitors of human leukocyte elastase
(Elsevier, 1993-08-07)A series of 3-(alkylthio)-N-hydroxysuccinimide derivatives was synthesized and their inhibitory activity towards human leukocyte elastase (HLE) was investigated. The interaction of the compounds having a 3-alkylthioether ... -
3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice
(NLM (Medline), 2020-08-19)Pathogenic coronaviruses are a major threat to global public health, as exemplified by severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), and the newly emerged ... -
3S-fluoroproline as a probe to monitor proline isomerization during protein folding by 19F-NMR
(Royal Society of Chemistry, 2009-06-21)Variable-temperature inversion transfer NMR is used to determine the kinetic and thermodynamic parameters of cis-trans isomerization of N-Ac-(3R) and (3S)-fluoroproline-OMe. -
A brief note on second-order community satisfaction factors for two sub-communities in Istanbul, Turkey
(Wichita State University, Department of Psychology, 1990)First-order Community Satisfaction factors obtained for a sample of residents of Istanbul, Turkey, were subjected to second-order factor analysis; a solution with two oblique factors ("General Satisfaction" and ... -
A brief note on second-order community satisfaction factors for two sub-communities in Istanbul, Turkey
(Wichita State University. Department of Psychology, 1990)Fiest-order Community Satisfaction factors obtained for a sample of residents of Istanbul, Turkey, were subjected to second-order factor analysis; a solution with two oblique factors ("General Satisfaction" and ... -
A call for Social Work students in mine action
(Wichita State University, School of Social Work, 2016-02-19)For too many, physical and psychological trauma are the unfortunate consequences of living in post-conflict regions where landmines and explosive remnants of war (ERW) continue to litter roads, farmland, and other critical ... -
A class of stationary random fields with a simple correlation structure
(Academic Press, 2004-07-15)A stationary random field is often more complicated than a univariate stationary time series, since dependence for a random field extends in all directions, while there is only the natural distinction of past and future ... -
A comparison of sanctions in African American and white TANF leavers
(Taylor & Francis, 2012-07)In this study the authors explore racial disparities in the uses of sanctions and the different impact of sanctions on the economic well-being of African American and White TANF leavers. The study analyzed 907 African ... -
A comparison of subsistence cultures and their interactions with non-human primates
(Wichita State University. Department of Anthropology, 2018)It is likely that 99% of human existence was spent as hunter-gatherers. While most academics approve of this fact, few agree on an explicit definition of hunter-gatherers. If defined through social organization, hunter-gatherers ... -
A comparison of two evaluation techniques for technical documentation
(Wichita State University, 2005-02)This study compared two evaluation techniques, Usability Testing and Cognitive Walkthrough, in their ability to identify errors in aviation maintenance documentation. The techniques were evaluated to see how much unique ... -
A culturally competent approach to engagement, assessment, intervention, and evaluation with LGBT elders: A case example
(Wichita State University, School of Social Work, 2015-05-28)The following is a case example that highlights some of the substantive issues that may be presented by a Lesbian, Gay, Bi-sexual, and Transgender [LGBT] older adult who is receiving mental health services. It offers ... -
A factor analysis of community satisfaction variables in a midwestern city
(Wichita State University, Department of Psychology, 1978)Community satisfaction in a midwestern city was examined through factor analysis; an oblique solution with nine factors resulted. Unlike previous research employing the same instruments and analytic techniques, distinctions ... -
A five-stage approach for improved use of citizen surveys in public investment decisions
(Sage Publications, 1994)Citizen surveys may be useful tools for enhancing government performance by leading to effective use of limited resources through responsiveness to citizen demand. This study develops a five-stage approach to citizen demand ... -
A model of the effect of interspecies competition for light on dry-matter production
(CSIRO Publishing, 1983-12)A model of the effect of interspecies competition for light on the daily dry-matter production of competing species is developed. It describes the absorption of light by the component species, accounting for their different ...