Browsing Fairmount College of Liberal Arts and Sciences by Subject "Pancreatic Elastase/blood"

Now showing items 1-3 of 3

Dual-action inhibitors of proteolytic enzymes: potential therapeutic agents for cystic fibrosis and related ailments

Groutas, William C.; Huang, He; Venkataraman, Radhika; Houser-Archield, Nadene; Epp, Jeffrey B. (Elsevier, 1993-10-01)
Hydantoin derivatives. A new class of inhibitors of human leukocyte elastase

Groutas, William C.; Stanga, Michael A.; Castrisos, J.C.; Schatz, E. J. (Informa Healthcare, 1990-01-01)

Derivatives of hydantoin have been found to inactivate human leukocyte elastase irreversibly. Chymotrypsin and cathepsin G are also inhibited by these compounds.
Substituted 3-oxo-1,2,5-thiadiazolidine 1,1-dioxides: a new class of potential mechanism-based inhibitors of human leukocyte elastase and cathepsin G

Groutas, William C.; Kuang, Rongze; Venkataraman, Radhika (Elsevier, 1994-01-14)

A series of substituted 3-oxo-1,2,5-thiadiazolidine 1,1-dioxides has been synthesized and their in vitro inhibitory activity toward human leukocyte elastase and cathepsin G was investigated. These compounds were found to ...