Browsing Fairmount College of Liberal Arts and Sciences by Subject "Oligosaccharide"

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Human FSH glycoform α-Subunit asparagine$^{52}$ glycans: Major glycan structural consistency, minor glycan variation in abundance

Butnev, Viktor Y.; May, Jeffrey V.; Brown, Alan R.; Sharma, Tarak; Butnev, Vladimir Y.; White, William K.; Harvey, David J.; Bousfield, George R. (Frontiers Media S.A., 2022-10-18)

Follicle-stimulating hormone (FSH), an α/β heterodimeric glycoprotein hormone, consists of functionally significant variants resulting from the presence or absence of either one of two FSHβ subunit N-glycans. The two most ...
Hypo-glycosylated human follicle-stimulating hormone (hFSH(21/18)) is much more active in vitro than fully-glycosylated hFSH (hFSH(24))

Bousfield, George R.; Butnev, Vladimir Y.; Butnev, Viktor Y.; Hiromasa, Yasuaki; Harvey, David J.; May, Jeffrey V. (Elsevier Ireland Ltd, 2014-02-15)

Hypo-glycosylated hFSH21/18 (possesses FSHβ21 and FSHβ18bands) was isolated from hLH preparations by immunoaffinity chromatography followed by gel filtration. Fully-glycosylated hFSH24 was prepared by combining the ...