Browsing Fairmount College of Liberal Arts and Sciences by Subject "FAIMS"
Now showing items 1-4 of 4
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Broad separation of isomeric lipids by high-resolution differential ion mobility spectrometry with tandem mass spectrometry
(Springer, 2017-08)Maturation of metabolomics has brought a deeper appreciation for the importance of isomeric identity of lipids to their biological role, mirroring that for proteoforms in proteomics. However, full characterization of the ... -
Disentangling lipid isomers by high-resolution differential ion mobility spectrometry/ozone-induced dissociation of metalated species
(American Chemical Society, 2021-11-09)The preponderance and functional importance of isomeric biomolecules have become topical in biochemistry. Therefore, one must distinguish and identify all such forms across compound classes, over a wide dynamic range as ... -
Identification of isomers by multidimensional isotopic shifts in high-field ion mobility spectra
(American Chemical Society, 2018-07-03)Nearly all molecules incorporate elements with stable isotopes. The resulting isotopologue envelopes in mass spectra tell the exact stoichiometry but nothing about the geometry. Chromatography and electrophoresis at high ... -
Localization of post-translational modifications in peptide mixtures via high-resolution differential ion mobility separations followed by electron transfer dissociation
(Springer International Publishing, 2016-12)Precise localization of post-translational modifications (PTMs) on proteins and peptides is an outstanding challenge in proteomics. While electron transfer dissociation (ETD) has dramatically advanced PTM analyses, mixtures ...