• Login
    View Item 
    •   Shocker Open Access Repository Home
    • Fairmount College of Liberal Arts and Sciences
    • Biological Sciences
    • BIO Faculty Scholarship
    • BIO Faculty Publications
    • View Item
    •   Shocker Open Access Repository Home
    • Fairmount College of Liberal Arts and Sciences
    • Biological Sciences
    • BIO Faculty Scholarship
    • BIO Faculty Publications
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Tolerogenic dendritic cells and rheumatoid arthritis: current status and perspectives

    View/Open
    Review (400.8Kb)
    Date
    2012-04
    Author
    Zhao, Yunpeng
    Zhang, Aijun
    Du, Hongxia
    Guo, Shuya
    Ning, Bin
    Yang, Shang-You
    Metadata
    Show full item record
    Citation
    Zhao, Yunpeng, Aijun Zhang, Hongxia Du, Shuya Guo, Bin Ning, and Shangyou Yang. 2012. "Tolerogenic dendritic cells and rheumatoid arthritis: current status and perspectives". Rheumatology International. 32 (4): 837-844.
    Abstract
    Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by the influxation of synovia and synovial compartments with immune cells including dendritic cells (DCs). DCs that induce autoimmune tolerance are called tolerogenic DCs (tolDCs). As a promising immunotherapeutic strategy for RA, tolDCs have received increasing attention. In this review, we first introduce the significant role of tolDCs in autoimmune regulation and then describe the manipulation strategies to generate tolDCs; next, we summarize recent progress in the experimental application of tolDCs for RA therapy, and finally we discuss the perspectives of tolerogenic vaccination for the treatment for RA in clinic.
    Description
    Click on the DOI link below to access the review article (may not be free).
    URI
    http://hdl.handle.net/10057/5088
    http://dx.doi.org/10.1007/s00296-011-2133-2
    Collections
    • BIO Faculty Publications

    Browse

    All of Shocker Open Access RepositoryCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsBy TypeThis CollectionBy Issue DateAuthorsTitlesSubjectsBy Type

    My Account

    LoginRegister

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    DSpace software copyright © 2002-2022  DuraSpace
    DSpace Express is a service operated by 
    Atmire NV