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dc.contributorWichita State University. Department of Physical Therapyen_US
dc.contributor.authorPitetti, Kenneth H.en_US
dc.contributor.authorClimstein, Mikeen_US
dc.contributor.authorCampbell, Kathryn D.en_US
dc.contributor.authorBarrett, Pamela J.en_US
dc.contributor.authorJackson, James A.en_US
dc.identifier.citationMedicine and science in sports and exercise. 1992 Jan; 24(1): 13-9.en_US
dc.descriptionThe full text of this article is not available in SOAR. Check the journal record for the paper version of the article in the library.en_US
dc.description.abstractThe purpose of this study was to compare the cardiovascular capacities of individuals with Down syndrome (DS) to individuals without Down syndrome who are mentally retarded. Sixteen young adults with DS and 16 individuals without DS (12 males and 4 females, respectively), all with mild/moderate mental retardation, participated in this study. Peak VO2 (absolute and relative), VE (1.min-1), heart rate (HR, b.min-1), and RER (VCO2/VO2) were determined by exercise tests utilizing a treadmill (TM) and Schwinn Air-Dyne ergometer (SAE). The best test result was chosen from the TM and SAE tests and used for statistical comparisons. Cardiac output (Q, 1.min-1) was measured while standing quietly and while walking at 3 mph, 0% grade, using the CO2 rebreathing method for 11 (9 males and 2 females) subjects from each group. Arteriovenous oxygen differences (a-v O2), cardiac index (QI), and stroke volume (SV) were calculated from VO2, Q, HR, and body surface area. Peripheral vascular resistance (PVR), left ventricular work index (LVWI), and left ventricular stroke work index (LVSWI) were calculated from mean arterial pressure, Q, QI, and stroke volume index. Results showed that individuals without DS had statistically significant (P less than 0.01) higher mean peak VO2 (35.6 vs 24.6; 2567 vs 1683 ml.min-1), VE (89.3 vs 59.2 1/min-1), and HR (179 vs 159 b.min-1) than individuals with DS, respectively. No differences in RER were seen between the groups. No differences were seen in cardiovascular parameters measured while quietly standing.(ABSTRACT TRUNCATED AT 250 WORDS)en_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofseriesMedicine and Science In Sports and Exerciseen_US
dc.relation.ispartofseriesMed Sci Sports Exercen_US
dc.subjectComparative Studyen_US
dc.subject.meshCardiovascular System/physiopathologyen_US
dc.subject.meshDown Syndrome/physiopathologyen_US
dc.subject.meshExercise Testen_US
dc.subject.meshIntellectual Disability/physiopathologyen_US
dc.subject.meshOxygen Consumptionen_US
dc.subject.meshPhysical Fitnessen_US
dc.subject.meshDown Syndrome/geneticsen_US
dc.titleThe cardiovascular capacities of adults with Down syndrome: a comparative studyen_US
dc.coverage.spacialUnited Statesen_US
dc.description.versionpeer revieweden_US
dc.rights.holderCopyright © Lippincott Williams & Wilkinsen_US

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