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dc.contributorWichita State University. Department of Physical Therapyen_US
dc.contributor.authorSmith, Barbara S.en_US
dc.contributor.authorWalker, N. J.en_US
dc.date.accessioned2012-03-12T19:12:28Z
dc.date.available2012-03-12T19:12:28Z
dc.date.issued1992-12en_US
dc.identifier1290159en_US
dc.identifier0153257en_US
dc.identifier.citationTeratology. 1992 Dec; 46(6): 583-98.en_US
dc.identifier.issn0040-3709en_US
dc.identifier.urihttp://dx.doi.org/10.1002/tera.1420460608en_US
dc.identifier.urihttp://hdl.handle.net/10057/4784
dc.descriptionClick on the DOI link below to access the article (may not be free).en_US
dc.description.abstractThe lenses and head mesenchyme of two 11-gestational day trisomy 1 mouse embryos and a normal littermate were examined using transmission electron microscopy (TEM). One trisomic embryo had a small lens with a lens stalk; the other was aphakic. The resolution available with TEM allowed detailed evaluation of cell organelles, spatial relationships and the intra- and extracellular structural environment of the lens and head mesenchyme in normal and aneuploid embryos. Differences in fine structure between normal and trisomic lenses included (1) type of epithelium, (2) size of intercellular lacunae, and (3) activity of Golgi complexes. Differences in mesenchyme included (1) the number and size of cytoplasmic extensions, (2) shape of the cells, and (3) reduced endotheliomesenchymal interactions.en_US
dc.format.extent583-98en_US
dc.language.isoengen_US
dc.publisherJohn Wiley & Sonsen_US
dc.relation.ispartofseriesTeratologyen_US
dc.relation.ispartofseriesTeratologyen_US
dc.sourceNLMen_US
dc.subjectComparative Studyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCell Sizeen_US
dc.subject.meshEpithelium/ultrastructureen_US
dc.subject.meshGestational Ageen_US
dc.subject.meshGolgi Apparatus/ultrastructureen_US
dc.subject.meshLens, Crystalline/abnormalitiesen_US
dc.subject.meshMesoderm/ultrastructureen_US
dc.subject.meshMiceen_US
dc.subject.meshTrisomyen_US
dc.subject.meshLens, Crystalline/embryologyen_US
dc.subject.meshLens, Crystalline/ultrastructureen_US
dc.titleLens and mesenchyme ultrastructure in gestational day 11 trisomy 1 miceen_US
dc.typeArticleen_US
dc.coverage.spacialUnited Statesen_US
dc.description.versionpeer revieweden_US
dc.rights.holderCopyright © 1992 Wiley-Lissen_US


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