• Login
    View Item 
    •   Shocker Open Access Repository Home
    • Graduate Student Research
    • The Capitol Graduate Research Summit in Topeka
    • 2006 WSU Annual CGRS Abstracts
    • View Item
    •   Shocker Open Access Repository Home
    • Graduate Student Research
    • The Capitol Graduate Research Summit in Topeka
    • 2006 WSU Annual CGRS Abstracts
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    A model for prostate cryoablation

    View/Open
    Abstract (20.55Kb)
    Date
    2006-03-08
    Author
    Ashton, John A.
    Metadata
    Show full item record
    Abstract
    One area of male specific health issues would certainly be disease affecting the prostate. Three main prostatic ailments include Prostatitis, Benign Prostatic Hyperplasia (BPH), and Cancer. Prostate cancer is the most common malignant form of cancer in men in the Western world. Treatment via radical prostatectomy can have serious complications and has resulted in the use of thermal therapies such as microwave, cryotherapy, and laser methods. Cryoablation, a form of cryotherapy, can be used to destroy cancer cells within the prostate. This therapy involves the controlled freezing to cellular kill temperatures of -40 0 C. Ice nodules that form in the -40 o C temperature range will effectively kill cancerous cells and if a steep temperature gradient can be attained it will allow the edge of the hard frozen tissue to virtually reach out to the extremities of the prostate. This project's goal is to provide a fast efficient and user-friendly modeling scheme that will allow individualized treatment and maximize temperature gradient at prostate extremities. Modeled time rate freeze development will enhance preoperative planning. Mathematical modeling provides a time dependent view of prostatic temperature gradient for various combinations of probe quantities, placement, and on/off ratios. Physical prostate sizing and selected probe quantities are entered into a spreadsheet that displays instantaneous graphical predictive results. The transient cooling rate calculations are based on bioheat equations and include automatic material phase change adjustments. Sample results based on average prostate sizing are also explored to estimate optimum probe spacing.
    Description
    The project completed at the Wichita State University Department of Mechanical Engineering. Presented at the 3rd Annual Capitol Graduate Research Summit, Topeka, KS, 2006.
    URI
    http://hdl.handle.net/10057/4737
    Collections
    • 2006 WSU Annual CGRS Abstracts

    Browse

    All of Shocker Open Access RepositoryCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsBy TypeThis CollectionBy Issue DateAuthorsTitlesSubjectsBy Type

    My Account

    LoginRegister

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    DSpace software copyright © 2002-2023  DuraSpace
    DSpace Express is a service operated by 
    Atmire NV