2-Fluoro-l-histidine
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Issue Date
2010-01-01
Embargo End Date
Authors
Andra, Kiran K.
Bullinger, John C.
Bann, James G.
Eichhorn, David M.
Advisor
Citation
Acta crystallographica. Section E, Structure reports online. 2010; 66(Pt 11): o2713.
Abstract
The title compound, C(6)H(8)FN(3)O(2), an analog of histidine, shows a reduced side-chain pK(a) (ca 1). The title structure exhibits a shortening of the bond between the proximal ring N atom and the F-substituted ring C atom, indicating an increase in p-bond character due to an inductive effect of fluorine.
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