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dc.contributorWichita State University. Department of Chemistryen_US
dc.contributor.authorDou, Dengfengen_US
dc.contributor.authorMandadapu, Sivakoteswara Raoen_US
dc.contributor.authorAlliston, Kevin R.en_US
dc.contributor.authorKim, Yunjeongen_US
dc.contributor.authorChang, Kyeong-Oken_US
dc.contributor.authorGroutas, William C.en_US
dc.date.accessioned2012-02-06T17:17:17Z
dc.date.available2012-02-06T17:17:17Z
dc.date.issued2011-10-01en_US
dc.identifier21893416en_US
dc.identifier9413298en_US
dc.identifierS0968-0896(11)00666-3en_US
dc.identifierAI081891en_US
dc.identifier.citationBioorganic & medicinal chemistry. 2011 Oct 1; 19(19): 5749-55.en_US
dc.identifier.issn1464-3391en_US
dc.identifier.issn0968-0896en_US
dc.identifier.urihttp://dx.doi.org/10.1016/j.bmc.2011.08.032en_US
dc.identifier.urihttp://hdl.handle.net/10057/4406
dc.descriptionClick on the DOI link below to access the article (may not be free).en_US
dc.description.abstractA scaffold hopping strategy was employed to identify new chemotypes that inhibit noroviruses. The replacement of the cyclosulfamide scaffold by an array of heterocyclic scaffolds lead to the identification of additional series of compounds that possessed anti-norovirus activity in a cell-based replicon system.en_US
dc.description.sponsorshipNIAID NIH HHSen_US
dc.format.extent5749-55en_US
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.relation.ispartofseriesBioorganic & medicinal chemistryen_US
dc.relation.ispartofseriesBioorg. Med. Chem.en_US
dc.sourceNLMen_US
dc.subjectResearch Support, N.I.H., Extramuralen_US
dc.titleDesign and synthesis of inhibitors of noroviruses by scaffold hoppingen_US
dc.typeArticleen_US
dc.coverage.spacialEnglanden_US
dc.description.versionpeer revieweden_US
dc.rights.holderCopyright © 2011, Elsevieren_US


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