Hydantoin derivatives. A new class of inhibitors of human leukocyte elastase

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Issue Date
1990-01-01
Embargo End Date
Authors
Groutas, William C.
Stanga, Michael A.
Castrisos, J.C.
Schatz, E. J.
Advisor
Citation

Journal of enzyme inhibition. 1990; 3(3): 237-43.

Abstract

Derivatives of hydantoin have been found to inactivate human leukocyte elastase irreversibly. Chymotrypsin and cathepsin G are also inhibited by these compounds.

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