Antifungal activity of a series of 1,2-benzisothiazol-3(2H)-one derivatives
Date
2011-10-01Author
Dou, Dengfeng
Alex, Deepu
Du, Bingfan
Tiew, Kok-Chuan
Aravapalli, Sridhar
Mandadapu, Sivakoteswara Rao
Calderone, Richard
Groutas, William C.
Metadata
Show full item recordCitation
Bioorganic & medicinal chemistry. 2011 Oct 1; 19(19): 5782-7.
Abstract
A series of broad-spectrum antifungal agents based on the 1,2-benzisothiazol-3(2H)-one scaffold is reported. Preliminary structure-activity relationship studies have established the importance of the presence of the heterocyclic ring, a methyl group, and a phenyl ring for optimal manifestation of antifungal activity.
Description
Click on the DOI link below to access the article (may not be free).