Antifungal activity of a series of 1,2-benzisothiazol-3(2H)-one derivatives
Mandadapu, Sivakoteswara Rao
Groutas, William C.
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Bioorganic & medicinal chemistry. 2011 Oct 1; 19(19): 5782-7.
A series of broad-spectrum antifungal agents based on the 1,2-benzisothiazol-3(2H)-one scaffold is reported. Preliminary structure-activity relationship studies have established the importance of the presence of the heterocyclic ring, a methyl group, and a phenyl ring for optimal manifestation of antifungal activity.
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